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Sensory and Sympathetic Nerves Control Blood Vessel Inflammation Through Neuropeptides

evidence
The takeaway

Peripheral sensory and sympathetic nerves regulated vascular ICAM-1 and selectin expression through neuropeptide release, demonstrating neural-vascular inflammation control relevant to atherosclerosis and inflammatory disease.

Key finding

Peripheral sensory and sympathetic nerves regulated vascular ICAM-1 and selectin expression through neuropeptide release, demonstrating neural-vascula

What the researchers found

Peripheral sensory and sympathetic nerves regulated vascular ICAM-1 and selectin expression through neuropeptide release, demonstrating neural-vascular inflammation control relevant to atherosclerosis and inflammatory disease.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Sensory and Sympathetic Nerves Control Blood Vessel Inflammation Through Neuropeptides
What was found?
Peripheral sensory and sympathetic nerves regulated vascular ICAM-1 and selectin expression through neuropeptide release, demonstrating neural-vascular inflammation control relevant to atherosclerosis and inflammatory disease.

Read the original research

Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.

Brain, behavior, and immunity, 24(8), 1310-23

Citation

Mousa, Shaaban A; Shaqura, Mohammed; Brendl, Ute; Al-Khrasani, Mahmoud; Fürst, Susanna; Schäfer, Michael. (2010). Involvement of the peripheral sensory and sympathetic nervous system in the vascular endothelial expression of ICAM-1 and the recruitment of opioid-containing immune cells to inhibit inflammatory pain.. Brain, behavior, and immunity, 24(8), 1310-23. https://doi.org/10.1016/j.bbi.2010.06.008