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Study breakdown

Des-Acyl Ghrelin Dilates Blood Vessels Through Potassium Channels — Without the Ghrelin Receptor

evidence
The takeaway

Des-acyl ghrelin fragments dilated rat blood vessels by activating potassium channels through a non-GHS-R1a pathway, confirming des-acyl ghrelin has its own vascular effects independent of the classical ghrelin receptor.

Key finding

Des-acyl ghrelin fragments dilated rat blood vessels by activating potassium channels through a non-GHS-R1a pathway, confirming des-acyl ghrelin has i

What the researchers found

Des-acyl ghrelin fragments dilated rat blood vessels by activating potassium channels through a non-GHS-R1a pathway, confirming des-acyl ghrelin has its own vascular effects independent of the classical ghrelin receptor.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Des-Acyl Ghrelin Dilates Blood Vessels Through Potassium Channels — Without the Ghrelin Receptor
What was found?
Des-acyl ghrelin fragments dilated rat blood vessels by activating potassium channels through a non-GHS-R1a pathway, confirming des-acyl ghrelin has its own vascular effects independent of the classical ghrelin receptor.

Read the original research

Des-acyl ghrelin fragments evoke endothelium-dependent vasodilatation of rat mesenteric vascular bed via activation of potassium channels.

European journal of pharmacology, 604(1-3), 79-86

Citation

Moazed, Banafsheh; Quest, Dale; Gopalakrishnan, Venkat. (2009). Des-acyl ghrelin fragments evoke endothelium-dependent vasodilatation of rat mesenteric vascular bed via activation of potassium channels.. European journal of pharmacology, 604(1-3), 79-86. https://doi.org/10.1016/j.ejphar.2008.10.032