S. pneumoniae's own protease PrtA paradoxically facilitated its killing by apolactoferrin, revealing that bacterial enzymes can inadvertently enhance antimicrobial protein activity against the bacteria themselves.
Key findingS. pneumoniae's own protease PrtA paradoxically facilitated its killing by apolactoferrin, revealing that bacterial enzymes can inadvertently enhance
What the researchers found
S. pneumoniae's own protease PrtA paradoxically facilitated its killing by apolactoferrin, revealing that bacterial enzymes can inadvertently enhance antimicrobial protein activity against the bacteria themselves.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.
Infection and immunity, 79(6), 2440-50
Citation
Mirza, Shaper; Wilson, Landon; Benjamin, William H; Novak, Jan; Barnes, Stephen; Hollingshead, Susan K; Briles, David E. (2011). Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.. Infection and immunity, 79(6), 2440-50. https://doi.org/10.1128/IAI.00489-10