Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.
Quick Facts
What This Study Found
In 32 men with HSDD, kisspeptin modulated sexual brain processing, enhanced penile tumescence to erotic videos, and increased happiness compared to placebo.
Key Numbers
32 men with HSDD; enhanced penile tumescence; increased happiness scores
How They Did This
Randomized, double-blind, placebo-controlled crossover trial with fMRI in men with HSDD.
Why This Research Matters
First RCT demonstrating kisspeptin's effects on sexual brain processing in men with clinical sexual dysfunction, showing both neural and physiological (tumescence) outcomes.
What This Study Doesn't Tell Us
Single session. Small sample. Same research group as prior studies.
Trust & Context
- Original Title:
- Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.
- Published In:
- JAMA network open, 6(2), e2255700 (2023)
- Authors:
- Mills, Edouard G(2), Dhillo, Waljit S(8)
- Database ID:
- RPEP-07181
Evidence Hierarchy
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-07181APA
Mills, Edouard G; Wall, Matthew B; Alexander, Emma C; Sherwood, Robin A; Sheridan, Rebecca; Byers, Alexander; Sherwood, Karolina; Clarke, Sophie A; Sheridan, Alexander; Salem, Victoria; Owen, Benedict M; Dhillo, Waljit S. (2023). Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.. JAMA network open, 6(2), e2255700. https://doi.org/10.1001/jamanetworkopen.2022.55700
MLA
Mills, Edouard G, et al. "Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.." JAMA network open, 2023. https://doi.org/10.1001/jamanetworkopen.2022.55700
RethinkPeptides
RethinkPeptides Research Database. "Effects of Kisspeptin on Sexual Brain Processing and Penile ..." RPEP-07181. Retrieved from https://rethinkpeptides.com/research/mills-2023-effects-of-kisspeptin-on-sexual
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.