This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
In 32 men with HSDD, kisspeptin modulated sexual brain processing, enhanced penile tumescence to erotic videos, and increased happiness compared to placebo.
Why it matters
First RCT demonstrating kisspeptin's effects on sexual brain processing in men with clinical sexual dysfunction, showing both neural and physiological (tumescence) outcomes.
The numbers in context
32 men with HSDD; enhanced penile tumescence; increased happiness scores
How the study worked
Randomized, double-blind, placebo-controlled crossover trial with fMRI in men with HSDD.
Who was studied
Men with hypoactive sexual desire disorder
What this study cannot tell us
Single session. Small sample. Same research group as prior studies.
Read the original research
Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.
JAMA network open, 6(2), e2255700
Citation
Mills, Edouard G; Wall, Matthew B; Alexander, Emma C; Sherwood, Robin A; Sheridan, Rebecca; Byers, Alexander; Sherwood, Karolina; Clarke, Sophie A; Sheridan, Alexander; Salem, Victoria; Owen, Benedict M; Dhillo, Waljit S. (2023). Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial.. JAMA network open, 6(2), e2255700. https://doi.org/10.1001/jamanetworkopen.2022.55700