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A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice.

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A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice.

The Journal of clinical investigation, 134(4)

Citation

Metzger, Peter J; Zhang, Aileen; Carlson, Bradley A; Sun, Hui; Cui, Zhenzhong; Li, Yongqi; Jahnke, Marshal T; Layton, Daniel R; Gupta, Meenakshi B; Liu, Naili; Kostenis, Evi; Gavrilova, Oksana; Chen, Min; Weinstein, Lee S. (2024). A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice.. The Journal of clinical investigation, 134(4). https://doi.org/10.1172/JCI165418