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Study breakdown

Rearranging the Small Intestine Changes How CCK Controls Appetite: Surgical Implications

evidence
The takeaway

Ileal interposition (moving a piece of lower intestine up) attenuated CCK-8 and CCK-33 satiety responses, showing that intestinal anatomical rearrangement changes gut peptide appetite signaling — bariatric surgery insight.

Key finding

Ileal interposition (moving a piece of lower intestine up) attenuated CCK-8 and CCK-33 satiety responses, showing that intestinal anatomical rearrange

What the researchers found

Ileal interposition (moving a piece of lower intestine up) attenuated CCK-8 and CCK-33 satiety responses, showing that intestinal anatomical rearrangement changes gut peptide appetite signaling — bariatric surgery insight.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Rearranging the Small Intestine Changes How CCK Controls Appetite: Surgical Implications
What was found?
Ileal interposition (moving a piece of lower intestine up) attenuated CCK-8 and CCK-33 satiety responses, showing that intestinal anatomical rearrangement changes gut peptide appetite signaling — bariatric surgery insight.

Read the original research

Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and -33.

Peptides, 32(6), 1296-302

Citation

Metcalf, Shannon A; Washington, Martha C; Brown, Thelma A L; Williams, Carol S; Strader, April D; Sayegh, Ayman I. (2011). Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and -33.. Peptides, 32(6), 1296-302. https://doi.org/10.1016/j.peptides.2011.04.023