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How Thymosin Alpha-1 Changes Gene Expression in Human Immune Cells: Transcription Profile

evidence
The takeaway

Thymosin alpha-1 treatment altered expression of hundreds of genes in human lymphocytes, including immune response, signaling, and metabolic genes — the most comprehensive transcriptional view of thymosin alpha-1's immune effects.

Key finding

Thymosin alpha-1 treatment altered expression of hundreds of genes in human lymphocytes, including immune response, signaling, and metabolic genes — t

What the researchers found

Thymosin alpha-1 treatment altered expression of hundreds of genes in human lymphocytes, including immune response, signaling, and metabolic genes — the most comprehensive transcriptional view of thymosin alpha-1's immune effects.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
How Thymosin Alpha-1 Changes Gene Expression in Human Immune Cells: Transcription Profile
What was found?
Thymosin alpha-1 treatment altered expression of hundreds of genes in human lymphocytes, including immune response, signaling, and metabolic genes — the most comprehensive transcriptional view of thymosin alpha-1's immune effects.

Read the original research

Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1.

Annals of the New York Academy of Sciences, 1194, 6-19

Citation

Matteucci, Claudia; Minutolo, Antonella; Sinibaldi-Vallebona, Paola; Palamara, Anna Teresa; Rasi, Guido; Mastino, Antonio; Garaci, Enrico. (2010). Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1.. Annals of the New York Academy of Sciences, 1194, 6-19. https://doi.org/10.1111/j.1749-6632.2010.05484.x