Early Maternal Separation Alters Mothering But Has Subtle Opioid Changes in Adult Offspring
Maternal separation altered maternal care behavior but produced only minor changes in adult offspring brain opioid peptide levels and behavior, suggesting resilience mechanisms partially compensate for early life adversity.
Quick Facts
What This Study Found
Maternal separation significantly altered maternal care patterns but produced only subtle changes in adult offspring brain opioid peptides and behavior, suggesting compensatory mechanisms partially buffer against early-life adversity effects.
Key Numbers
How They Did This
animal-study study on opioid-peptides, anxiety-mood.
Why This Research Matters
Relevant for opioid-peptides, anxiety-mood, addiction, neuropeptides.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Maternal separation significantly altered maternal care patterns but produced only subtle changes in adult offspring brain opioid peptides and behavio
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2004.
- Original Title:
- Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.
- Published In:
- Developmental psychobiology, 45(3), 140-52 (2004)
- Authors:
- Marmendal, Maarit, Roman, Erika(2), Eriksson, C J Peter, Nylander, Ingrid, Fahlke, Claudia
- Database ID:
- RPEP-00946
Evidence Hierarchy
Tests effects in animals (usually mice or rats), not humans.
What do these levels mean? →Frequently Asked Questions
What was studied?
Early Maternal Separation Alters Mothering But Has Subtle Opioid Changes in Adult Offspring
What was found?
Maternal separation altered maternal care behavior but produced only minor changes in adult offspring brain opioid peptide levels and behavior, suggesting resilience mechanisms partially compensate for early life adversity.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-00946APA
Marmendal, Maarit; Roman, Erika; Eriksson, C J Peter; Nylander, Ingrid; Fahlke, Claudia. (2004). Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.. Developmental psychobiology, 45(3), 140-52.
MLA
Marmendal, Maarit, et al. "Maternal separation alters maternal care, but has minor effects on behavior and brain opioid peptides in adult offspring.." Developmental psychobiology, 2004.
RethinkPeptides
RethinkPeptides Research Database. "Maternal separation alters maternal care, but has minor effe..." RPEP-00946. Retrieved from https://rethinkpeptides.com/research/marmendal-2004-maternal-separation-alters-maternal
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.