This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
C. regius-derived conotoxins show high potency and selectivity against nicotinic acetylcholine receptors.
Why it matters
Understanding and improving conotoxins could lead to new treatments for serious conditions like pain and addiction. Their unique properties make them valuable for drug development.
How the study worked
The study provides an overview of the pharmacological features and molecular mechanisms of conotoxins, along with proposed chemical engineering solutions.
What this study cannot tell us
The study highlights species-specific differences and the challenges of stability and bioavailability in clinical settings.
Read the original research
Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism.
Marine drugs, 20(12)
Citation
Margiotta, Francesco; Micheli, Laura; Ciampi, Clara; Ghelardini, Carla; McIntosh, J Michael; Di Cesare Mannelli, Lorenzo. (2022). Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism.. Marine drugs, 20(12). https://doi.org/10.3390/md20120773