Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.
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Trust & Context
- Original Title:
- Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.
- Published In:
- Diabetes, obesity & metabolism, 27(10), 5938-5949 (2025)
- Authors:
- Manchanda, Yusman, Jones, Ben(6), Carrat, Gaelle, Ramchunder, Zenouska, Marchetti, Piero, Leclerc, Isabelle, Thennati, Rajamannar, Burade, Vinod, Natarajan, Muthukumaran, Shahi, Pradeep, Tomas, Alejandra, Rutter, Guy A
- Database ID:
- RPEP-12426
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-12426APA
Manchanda, Yusman; Jones, Ben; Carrat, Gaelle; Ramchunder, Zenouska; Marchetti, Piero; Leclerc, Isabelle; Thennati, Rajamannar; Burade, Vinod; Natarajan, Muthukumaran; Shahi, Pradeep; Tomas, Alejandra; Rutter, Guy A. (2025). Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.. Diabetes, obesity & metabolism, 27(10), 5938-5949. https://doi.org/10.1111/dom.16652
MLA
Manchanda, Yusman, et al. "Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.." Diabetes, 2025. https://doi.org/10.1111/dom.16652
RethinkPeptides
RethinkPeptides Research Database. "Binding kinetics, bias, receptor internalization and effects..." RPEP-12426. Retrieved from https://rethinkpeptides.com/research/manchanda-2025-binding-kinetics-bias-receptor
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Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.