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Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.
Diabetes, obesity & metabolism, 27(10), 5938-5949
Citation
Manchanda, Yusman; Jones, Ben; Carrat, Gaelle; Ramchunder, Zenouska; Marchetti, Piero; Leclerc, Isabelle; Thennati, Rajamannar; Burade, Vinod; Natarajan, Muthukumaran; Shahi, Pradeep; Tomas, Alejandra; Rutter, Guy A. (2025). Binding kinetics, bias, receptor internalization and effects on insulin secretion in vitro and in vivo of a novel GLP-1R/GIPR dual agonist, HISHS-2001.. Diabetes, obesity & metabolism, 27(10), 5938-5949. https://doi.org/10.1111/dom.16652