Pain persists in mice lacking both Substance P and CGRPα signaling.

MacDonald, Donald Iain et al.·eLife·2025·
RPEP-123792025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Key Numbers

How They Did This

Why This Research Matters

What This Study Doesn't Tell Us

Trust & Context

Original Title:
Pain persists in mice lacking both Substance P and CGRPα signaling.
Published In:
eLife, 13 (2025)
Database ID:
RPEP-12379

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
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Cite This Study

RPEP-12379·https://rethinkpeptides.com/research/RPEP-12379

APA

MacDonald, Donald Iain; Jayabalan, Monessha; Seaman, Jonathan T; Balaji, Rakshita; Nickolls, Alec R; Chesler, Alexander Theodore. (2025). Pain persists in mice lacking both Substance P and CGRPα signaling.. eLife, 13. https://doi.org/10.7554/eLife.93754

MLA

MacDonald, Donald Iain, et al. "Pain persists in mice lacking both Substance P and CGRPα signaling.." eLife, 2025. https://doi.org/10.7554/eLife.93754

RethinkPeptides

RethinkPeptides Research Database. "Pain persists in mice lacking both Substance P and CGRPα sig..." RPEP-12379. Retrieved from https://rethinkpeptides.com/research/macdonald-2025-pain-persists-in-mice

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Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.