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Breaking disulfide bonds in a weakly bactericidal α-defensin unleashes a potent antimicrobial peptide with an altered conformation.

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Breaking disulfide bonds in a weakly bactericidal α-defensin unleashes a potent antimicrobial peptide with an altered conformation.

PLoS pathogens, 22(2), e1013954

Citation

Luo, Gan; Zhao, Mingzhu; Wang, Qingxia; Zhou, Yang; Yao, Dan; Zhang, Jue; Wang, Gang; Zhang, Junjie; Liao, Chongbing; Lu, Wuyuan. (2026). Breaking disulfide bonds in a weakly bactericidal α-defensin unleashes a potent antimicrobial peptide with an altered conformation.. PLoS pathogens, 22(2), e1013954. https://doi.org/10.1371/journal.ppat.1013954