Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.

Lisowska, Barbara et al.·PloS one·2015·
RPEP-027182015RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Serum substance P concentrations were significantly different between osteoarthritis and rheumatoid arthritis patients and positively correlated with chronic pain intensity in both groups.

Key Numbers

How They Did This

The study enrolled patients diagnosed with osteoarthritis and rheumatoid arthritis and measured their serum substance P levels. Pain intensity was assessed and correlated with substance P concentrations to evaluate their relationship.

Why This Research Matters

Understanding the link between substance P and chronic pain could help develop targeted treatments for inflammatory joint diseases, improving pain management.

What This Study Doesn't Tell Us

The study type and evidence strength were not specified, and the sample size and control details are unclear, limiting the ability to generalize findings.

Trust & Context

Original Title:
Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.
Published In:
PloS one, 10(10), e0139206 (2015)
Database ID:
RPEP-02718

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

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Cite This Study

RPEP-02718·https://rethinkpeptides.com/research/RPEP-02718

APA

Lisowska, Barbara; Lisowski, Aleksander; Siewruk, Katarzyna. (2015). Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.. PloS one, 10(10), e0139206. https://doi.org/10.1371/journal.pone.0139206

MLA

Lisowska, Barbara, et al. "Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.." PloS one, 2015. https://doi.org/10.1371/journal.pone.0139206

RethinkPeptides

RethinkPeptides Research Database. "Substance P and Chronic Pain in Patients with Chronic Inflam..." RPEP-02718. Retrieved from https://rethinkpeptides.com/research/lisowska-2015-substance-p-and-chronic

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.