Inflammation conferred dual effects on chronic neuropathic pain: initially worsening via neuroinflammation but also providing opioid-mediated relief through immune cell opioid peptide release — a paradoxical anti-/pronociceptive balance.
Key findingInflammation conferred dual effects on chronic neuropathic pain: initially worsening via neuroinflammation but also providing opioid-mediated relief t
What the researchers found
Inflammation conferred dual effects on chronic neuropathic pain: initially worsening via neuroinflammation but also providing opioid-mediated relief through immune cell opioid peptide release — a paradoxical anti-/pronociceptive balance.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Inflammation confers dual effects on nociceptive processing in chronic neuropathic pain model.
Anesthesiology, 114(3), 660-72
Citation
Liou, Jiin-Tarng; Liu, Fu-Chao; Mao, Chih-Chieh; Lai, Ying-Shu; Day, Yuan-Ji. (2011). Inflammation confers dual effects on nociceptive processing in chronic neuropathic pain model.. Anesthesiology, 114(3), 660-72. https://doi.org/10.1097/ALN.0b013e31820b8b1e