A homogeneous time-resolved fluorescence assay was developed for high-throughput screening of GHS-R1a ligands, enabling rapid identification of novel ghrelin receptor drug candidates for obesity and GH deficiency.
Key findingA homogeneous time-resolved fluorescence assay was developed for high-throughput screening of GHS-R1a ligands, enabling rapid identification of novel
What the researchers found
A homogeneous time-resolved fluorescence assay was developed for high-throughput screening of GHS-R1a ligands, enabling rapid identification of novel ghrelin receptor drug candidates for obesity and GH deficiency.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.
Analytical biochemistry, 408(2), 253-62
Citation
Leyris, Jean-Philippe; Roux, Thomas; Trinquet, Eric; Verdié, Pascal; Fehrentz, Jean-Alain; Oueslati, Nadia; Douzon, Stéphanie; Bourrier, Emmanuel; Lamarque, Laurent; Gagne, Didier; Galleyrand, Jean-Claude; M'kadmi, Céline; Martinez, Jean; Mary, Sophie; Banères, Jean-Louis; Marie, Jacky. (2011). Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.. Analytical biochemistry, 408(2), 253-62. https://doi.org/10.1016/j.ab.2010.09.030