rethinkPeptides Search
Menu
Study breakdown

Targeting the Ghrelin System for Alcoholism: A New Approach to Alcohol Use Disorder

evidence
The takeaway

The ghrelin system offers a novel therapeutic target for alcoholism — ghrelin receptor antagonists could reduce alcohol craving and consumption by blocking the hunger hormone's reward-promoting effects.

Key finding

The ghrelin system offers a novel therapeutic target for alcoholism — ghrelin receptor antagonists could reduce alcohol craving and consumption by blo

What the researchers found

The ghrelin system offers a novel therapeutic target for alcoholism — ghrelin receptor antagonists could reduce alcohol craving and consumption by blocking the hunger hormone's reward-promoting effects.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Targeting the Ghrelin System for Alcoholism: A New Approach to Alcohol Use Disorder
What was found?
The ghrelin system offers a novel therapeutic target for alcoholism — ghrelin receptor antagonists could reduce alcohol craving and consumption by blocking the hunger hormone's reward-promoting effects.

Read the original research

Role of the ghrelin system in alcoholism: Acting on the growth hormone secretagogue receptor to treat alcohol-related diseases.

Drug news & perspectives, 23(3), 157-66

Citation

Leggio, L. (2010). Role of the ghrelin system in alcoholism: Acting on the growth hormone secretagogue receptor to treat alcohol-related diseases.. Drug news & perspectives, 23(3), 157-66. https://doi.org/10.1358/dnp.2010.23.3.1429490