The two fold role of oxytocin in social developmental disorders: A cause and a remedy?

Lefevre, Arthur et al.·Neuroscience and biobehavioral reviews·2016·
RPEP-030082016RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Early oxytocin administration may be associated with social developmental impairments such as autism spectrum disorders, but oxytocin also shows potential to improve social behaviors in ASD patients. Animal studies reveal contradictory effects of chronic oxytocin exposure, highlighting complex biological mechanisms.

Key Numbers

How They Did This

This article is a literature review analyzing recent animal and human studies on the long-term effects of neonatal and chronic oxytocin administration on social development and autism spectrum disorders.

Why This Research Matters

Understanding oxytocin's dual role is crucial for safely using it in obstetrics and exploring its therapeutic potential for social impairments in autism.

What This Study Doesn't Tell Us

The evidence is largely based on animal studies with contradictory results, and human data are methodologically limited, making definitive conclusions difficult.

Trust & Context

Original Title:
The two fold role of oxytocin in social developmental disorders: A cause and a remedy?
Published In:
Neuroscience and biobehavioral reviews, 63, 168-76 (2016)
Database ID:
RPEP-03008

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

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Cite This Study

RPEP-03008·https://rethinkpeptides.com/research/RPEP-03008

APA

Lefevre, Arthur; Sirigu, Angela. (2016). The two fold role of oxytocin in social developmental disorders: A cause and a remedy?. Neuroscience and biobehavioral reviews, 63, 168-76. https://doi.org/10.1016/j.neubiorev.2016.01.011

MLA

Lefevre, Arthur, et al. "The two fold role of oxytocin in social developmental disorders: A cause and a remedy?." Neuroscience and biobehavioral reviews, 2016. https://doi.org/10.1016/j.neubiorev.2016.01.011

RethinkPeptides

RethinkPeptides Research Database. "The two fold role of oxytocin in social developmental disord..." RPEP-03008. Retrieved from https://rethinkpeptides.com/research/lefevre-2016-the-two-fold-role

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Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.