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Study breakdown

Mitochondria-Targeted Peptide Prevents Burn-Induced Gut Cell Death and ER Stress

evidence
The takeaway

A novel mitochondria-targeted antioxidant peptide (SS-31 family) prevented burn-induced intestinal epithelial apoptosis and ER stress — protecting the gut barrier from thermal injury through mitochondrial preservation.

Key finding

A novel mitochondria-targeted antioxidant peptide (SS-31 family) prevented burn-induced intestinal epithelial apoptosis and ER stress — protecting the

What the researchers found

A novel mitochondria-targeted antioxidant peptide (SS-31 family) prevented burn-induced intestinal epithelial apoptosis and ER stress — protecting the gut barrier from thermal injury through mitochondrial preservation.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Mitochondria-Targeted Peptide Prevents Burn-Induced Gut Cell Death and ER Stress
What was found?
A novel mitochondria-targeted antioxidant peptide (SS-31 family) prevented burn-induced intestinal epithelial apoptosis and ER stress — protecting the gut barrier from thermal injury through mitochondrial preservation.

Read the original research

Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice.

Shock (Augusta, Ga.), 36(6), 580-5

Citation

Lee, Hyung-yul; Kaneki, Masao; Andreas, Jonathan; Tompkins, Ronald G; Martyn, J A Jeevendra. (2011). Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice.. Shock (Augusta, Ga.), 36(6), 580-5. https://doi.org/10.1097/SHK.0b013e3182366872