The ghrelin receptor's constitutive activity (signaling without ghrelin) protected cells from apoptosis through a PKC-dependent survival pathway — the receptor's baseline activity has its own biological function.
Key findingThe ghrelin receptor's constitutive activity (signaling without ghrelin) protected cells from apoptosis through a PKC-dependent survival pathway — the
What the researchers found
The ghrelin receptor's constitutive activity (signaling without ghrelin) protected cells from apoptosis through a PKC-dependent survival pathway — the receptor's baseline activity has its own biological function.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway.
Molecular and cellular endocrinology, 299(2), 232-9
Citation
Lau, Pui Ngan; Chow, Kevin B S; Chan, Chi-Bun; Cheng, Christopher H K; Wise, Helen. (2009). The constitutive activity of the ghrelin receptor attenuates apoptosis via a protein kinase C-dependent pathway.. Molecular and cellular endocrinology, 299(2), 232-9. https://doi.org/10.1016/j.mce.2008.12.006