Ghrelin Gene Variants Linked to Heavy Drinking and Body Weight in Humans
Genetic polymorphisms in the pro-ghrelin and GHS-R1A genes were associated with heavy alcohol use and body mass in a human population study, linking ghrelin system genetics to both addiction and obesity risk.
Quick Facts
What This Study Found
Pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes were associated with heavy alcohol use and BMI in humans, providing genetic evidence linking the ghrelin system to both alcohol addiction vulnerability and body weight regulation.
Key Numbers
How They Did This
cross-sectional study.
Why This Research Matters
Relevant for neuropeptides, addiction, hormone-optimization.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding Pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes were associated with heavy alcohol use and BMI in humans, providing genetic evidence linking
- Evidence Grade:
- preliminary evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.
- Published In:
- Alcoholism, clinical and experimental research, 32(12), 2054-61 (2008)
- Authors:
- Landgren, Sara, Jerlhag, Elisabet(10), Zetterberg, Henrik, Gonzalez-Quintela, Arturo, Campos, Joaquin, Olofsson, Ulrica, Nilsson, Staffan, Blennow, Kaj, Engel, Jörgen A
- Database ID:
- RPEP-01373
Evidence Hierarchy
A snapshot of a population at one point in time.
What do these levels mean? →Frequently Asked Questions
What was studied?
Ghrelin Gene Variants Linked to Heavy Drinking and Body Weight in Humans
What was found?
Genetic polymorphisms in the pro-ghrelin and GHS-R1A genes were associated with heavy alcohol use and body mass in a human population study, linking ghrelin system genetics to both addiction and obesity risk.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01373APA
Landgren, Sara; Jerlhag, Elisabet; Zetterberg, Henrik; Gonzalez-Quintela, Arturo; Campos, Joaquin; Olofsson, Ulrica; Nilsson, Staffan; Blennow, Kaj; Engel, Jörgen A. (2008). Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.. Alcoholism, clinical and experimental research, 32(12), 2054-61. https://doi.org/10.1111/j.1530-0277.2008.00793.x
MLA
Landgren, Sara, et al. "Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.." Alcoholism, 2008. https://doi.org/10.1111/j.1530-0277.2008.00793.x
RethinkPeptides
RethinkPeptides Research Database. "Association of pro-ghrelin and GHS-R1A gene polymorphisms an..." RPEP-01373. Retrieved from https://rethinkpeptides.com/research/landgren-2008-association-of-proghrelin-and
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.