Tear neuromediator levels (substance P, CGRP, NPY, VIP) were altered in dry eye disease patients, revealing neuropeptide imbalance as a component of dry eye pathophysiology — potential biomarkers and therapeutic targets.
Key findingTear neuromediator levels (substance P, CGRP, NPY, VIP) were altered in dry eye disease patients, revealing neuropeptide imbalance as a component of d
What the researchers found
Tear neuromediator levels (substance P, CGRP, NPY, VIP) were altered in dry eye disease patients, revealing neuropeptide imbalance as a component of dry eye pathophysiology — potential biomarkers and therapeutic targets.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Alterations of tear neuromediators in dry eye disease.
Archives of ophthalmology (Chicago, Ill. : 1960), 129(8), 981-6
Citation
Lambiase, Alessandro; Micera, Alessandra; Sacchetti, Marta; Cortes, Magdalena; Mantelli, Flavio; Bonini, Stefano. (2011). Alterations of tear neuromediators in dry eye disease.. Archives of ophthalmology (Chicago, Ill. : 1960), 129(8), 981-6. https://doi.org/10.1001/archophthalmol.2011.200