GHRP-2 Increases Food Intake in Healthy Men — Confirming the Appetite Side Effect in Humans

Intravenous GHRP-2 significantly increased food intake and hunger ratings in healthy men alongside GH release, directly confirming the orexigenic effect of GH secretagogues in humans — not just animals.

Laferrère, Blandine et al.·The Journal of clinical endocrinology and metabolism·2005·Moderate Evidenceclinical-trial
RPEP-01060Clinical TrialModerate Evidence2005RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
clinical-trial
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

IV GHRP-2 increased food intake by ~35% and hunger VAS scores in healthy men in a controlled study, directly confirming the appetite-stimulating effect of GH secretagogues in humans alongside potent GH/cortisol release.

Key Numbers

How They Did This

clinical-trial study on ghrp, hormone-optimization.

Why This Research Matters

Relevant for ghrp, hormone-optimization.

The Bigger Picture

Advances peptide research with clinical implications.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding IV GHRP-2 increased food intake by ~35% and hunger VAS scores in healthy men in a controlled study, directly confirming the appetite-stimulating effec
Evidence Grade:
moderate evidence.
Study Age:
Published in 2005.
Original Title:
Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.
Published In:
The Journal of clinical endocrinology and metabolism, 90(2), 611-4 (2005)
Database ID:
RPEP-01060

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

GHRP-2 Increases Food Intake in Healthy Men — Confirming the Appetite Side Effect in Humans

What was found?

Intravenous GHRP-2 significantly increased food intake and hunger ratings in healthy men alongside GH release, directly confirming the orexigenic effect of GH secretagogues in humans — not just animals.

Read More on RethinkPeptides

Cite This Study

RPEP-01060·https://rethinkpeptides.com/research/RPEP-01060

APA

Laferrère, Blandine; Abraham, Cynthia; Russell, Colleen D; Bowers, Cyril Y. (2005). Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.. The Journal of clinical endocrinology and metabolism, 90(2), 611-4.

MLA

Laferrère, Blandine, et al. "Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.." The Journal of clinical endocrinology and metabolism, 2005.

RethinkPeptides

RethinkPeptides Research Database. "Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, i..." RPEP-01060. Retrieved from https://rethinkpeptides.com/research/laferrere-2005-growth-hormone-releasing-peptide2

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.