GHRP-2, CRF, and desmopressin each produced distinct ACTH response patterns (concordant vs discordant with cortisol), revealing how different peptide stimuli engage the stress axis through different mechanisms.
Key findingGHRP-2, CRF, and desmopressin each produced distinct ACTH response patterns (concordant vs discordant with cortisol), revealing how different peptide
What the researchers found
GHRP-2, CRF, and desmopressin each produced distinct ACTH response patterns (concordant vs discordant with cortisol), revealing how different peptide stimuli engage the stress axis through different mechanisms.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Concordant and discordant adrenocorticotropin (ACTH) responses induced by growth hormone-releasing peptide-2 (GHRP-2), corticotropin-releasing hormone (CRH) and insulin-induced hypoglycemia in patients with hypothalamopituitary disorders: evidence for direct ACTH releasing activity of GHRP-2.
Endocrine journal, 57(7), 639-44
Citation
Kimura, Takashi; Shimatsu, Akira; Arimura, Hiroshi; Mori, Hideki; Tokitou, Akinori; Fukudome, Michiyo; Nakazaki, Mitsuhiro; Tei, Chuwa. (2010). Concordant and discordant adrenocorticotropin (ACTH) responses induced by growth hormone-releasing peptide-2 (GHRP-2), corticotropin-releasing hormone (CRH) and insulin-induced hypoglycemia in patients with hypothalamopituitary disorders: evidence for direct ACTH releasing activity of GHRP-2.. Endocrine journal, 57(7), 639-44.