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Study breakdown

Producing GLP-1 Protein in Bacteria: Recombinant Manufacturing for the Diabetes Drug Peptide

evidence
The takeaway

Human GLP-1 was produced and correctly refolded from recombinant E. coli, establishing bacterial expression as a manufacturing platform for this important diabetes drug peptide.

Key finding

Human GLP-1 was produced and correctly refolded from recombinant E. coli, establishing bacterial expression as a manufacturing platform for this impor

What the researchers found

Human GLP-1 was produced and correctly refolded from recombinant E. coli, establishing bacterial expression as a manufacturing platform for this important diabetes drug peptide.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Producing GLP-1 Protein in Bacteria: Recombinant Manufacturing for the Diabetes Drug Peptide
What was found?
Human GLP-1 was produced and correctly refolded from recombinant E. coli, establishing bacterial expression as a manufacturing platform for this important diabetes drug peptide.

Read the original research

Production and solid-phase refolding of human glucagon-like peptide-1 using recombinant Escherichia coli.

Protein expression and purification, 78(2), 197-203

Citation

Kim, Sung-Gun; Shin, So-Yeon; Park, Yong-Cheol; Shin, Chul-Soo; Seo, Jin-Ho. (2011). Production and solid-phase refolding of human glucagon-like peptide-1 using recombinant Escherichia coli.. Protein expression and purification, 78(2), 197-203. https://doi.org/10.1016/j.pep.2011.03.008