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Radioactive Peptide Probe for Detecting Cancer Tumors via c-Met Receptor Imaging

evidence
The takeaway

A Tc-99m labeled triazole peptide binding c-Met receptor kinase was synthesized for tumor imaging, enabling detection of c-Met-positive cancers through nuclear medicine — peptide-based cancer diagnostics.

Key finding

A Tc-99m labeled triazole peptide binding c-Met receptor kinase was synthesized for tumor imaging, enabling detection of c-Met-positive cancers throug

What the researchers found

A Tc-99m labeled triazole peptide binding c-Met receptor kinase was synthesized for tumor imaging, enabling detection of c-Met-positive cancers through nuclear medicine — peptide-based cancer diagnostics.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Radioactive Peptide Probe for Detecting Cancer Tumors via c-Met Receptor Imaging
What was found?
A Tc-99m labeled triazole peptide binding c-Met receptor kinase was synthesized for tumor imaging, enabling detection of c-Met-positive cancers through nuclear medicine — peptide-based cancer diagnostics.

Read the original research

Synthesis of Tc-99m labeled 1,2,3-triazole-4-yl c-met binding peptide as a potential c-met receptor kinase positive tumor imaging agent.

Bioorganic & medicinal chemistry letters, 20(14), 4240-3

Citation

Kim, Eun-Mi; Joung, Min-Hee; Lee, Chang-Moon; Jeong, Hwan-Jeong; Lim, Seok Tae; Sohn, Myung-Hee; Kim, Dong Wook. (2010). Synthesis of Tc-99m labeled 1,2,3-triazole-4-yl c-met binding peptide as a potential c-met receptor kinase positive tumor imaging agent.. Bioorganic & medicinal chemistry letters, 20(14), 4240-3. https://doi.org/10.1016/j.bmcl.2010.05.036