Apelin and ACE2 in Heart Disease: Two Protective Peptide Systems Working Together
Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation — together opposing the harmful renin-angiotensin system.
Quick Facts
What This Study Found
Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation — together opposing the harmful renin-angiotensin system.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2010.
- Original Title:
- Apelin and ACE2 in cardiovascular disease.
- Published In:
- Current opinion in investigational drugs (London, England : 2000), 11(3), 273-82 (2010)
- Authors:
- Kalea, Anastasia Z, Batlle, Daniel
- Database ID:
- RPEP-01637
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Apelin and ACE2 in Heart Disease: Two Protective Peptide Systems Working Together
What was found?
Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation — together opposing the harmful renin-angiotensin system.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01637APA
Kalea, Anastasia Z; Batlle, Daniel. (2010). Apelin and ACE2 in cardiovascular disease.. Current opinion in investigational drugs (London, England : 2000), 11(3), 273-82.
MLA
Kalea, Anastasia Z, et al. "Apelin and ACE2 in cardiovascular disease.." Current opinion in investigational drugs (London, 2010.
RethinkPeptides
RethinkPeptides Research Database. "Apelin and ACE2 in cardiovascular disease." RPEP-01637. Retrieved from https://rethinkpeptides.com/research/kalea-2010-apelin-and-ace2-in
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.