Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation — together opposing the harmful renin-angiotensin system.
Key findingApelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation
What the researchers found
Apelin and ACE2 form a cardiovascular protective axis — apelin through vasodilation and cardiac contractility, ACE2 through angiotensin II degradation — together opposing the harmful renin-angiotensin system.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Apelin and ACE2 in cardiovascular disease.
Current opinion in investigational drugs (London, England : 2000), 11(3), 273-82
Citation
Kalea, Anastasia Z; Batlle, Daniel. (2010). Apelin and ACE2 in cardiovascular disease.. Current opinion in investigational drugs (London, England : 2000), 11(3), 273-82.