Cystine-Knot Peptide Scaffold Used for Cancer PET Imaging: Cyclotides as Diagnostic Tools
A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cyclotide scaffolds as stable cancer diagnostic imaging agents.
Quick Facts
What This Study Found
A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cyclotide scaffolds as stable cancer diagnostic imaging agents.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cycloti
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2010.
- Original Title:
- Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.
- Published In:
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(2), 251-258 (2010)
- Authors:
- Jiang, Lei(2), Kimura, Richard H, Miao, Zheng, Silverman, Adam P, Ren, Gang, Liu, Hongguang, Li, Peiyong, Gambhir, Sanjiv Sam, Cochran, Jennifer R, Cheng, Zhen
- Database ID:
- RPEP-01635
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Cystine-Knot Peptide Scaffold Used for Cancer PET Imaging: Cyclotides as Diagnostic Tools
What was found?
A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cyclotide scaffolds as stable cancer diagnostic imaging agents.
Read More on RethinkPeptides
Related articles coming soon.
Cite This Study
https://rethinkpeptides.com/research/RPEP-01635APA
Jiang, Lei; Kimura, Richard H; Miao, Zheng; Silverman, Adam P; Ren, Gang; Liu, Hongguang; Li, Peiyong; Gambhir, Sanjiv Sam; Cochran, Jennifer R; Cheng, Zhen. (2010). Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(2), 251-258. https://doi.org/10.2967/jnumed.109.069831
MLA
Jiang, Lei, et al. "Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.." Journal of nuclear medicine : official publication, 2010. https://doi.org/10.2967/jnumed.109.069831
RethinkPeptides
RethinkPeptides Research Database. "Evaluation of a (64)Cu-labeled cystine-knot peptide based on..." RPEP-01635. Retrieved from https://rethinkpeptides.com/research/jiang-2010-evaluation-of-a-64culabeled
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.