A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cyclotide scaffolds as stable cancer diagnostic imaging agents.
Key findingA cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cycloti
What the researchers found
A cystine-knot peptide based on agouti-related protein was labeled with 64Cu for PET imaging of tumors expressing αvβ3 integrin, demonstrating cyclotide scaffolds as stable cancer diagnostic imaging agents.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(2), 251-258
Citation
Jiang, Lei; Kimura, Richard H; Miao, Zheng; Silverman, Adam P; Ren, Gang; Liu, Hongguang; Li, Peiyong; Gambhir, Sanjiv Sam; Cochran, Jennifer R; Cheng, Zhen. (2010). Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(2), 251-258. https://doi.org/10.2967/jnumed.109.069831