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Study breakdown

Sugar Modifications on Pro-BNP Affect Its Stability and Processing: Clinical Assay Implications

evidence
The takeaway

Sialylated O-glycans on pro-BNP affected its stability and processing, with glycosylation influencing which molecular forms circulate — important for clinical BNP/NT-proBNP assay accuracy.

Key finding

Sialylated O-glycans on pro-BNP affected its stability and processing, with glycosylation influencing which molecular forms circulate — important for

What the researchers found

Sialylated O-glycans on pro-BNP affected its stability and processing, with glycosylation influencing which molecular forms circulate — important for clinical BNP/NT-proBNP assay accuracy.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Sugar Modifications on Pro-BNP Affect Its Stability and Processing: Clinical Assay Implications
What was found?
Sialylated O-glycans on pro-BNP affected its stability and processing, with glycosylation influencing which molecular forms circulate — important for clinical BNP/NT-proBNP assay accuracy.

Read the original research

Effect of sialylated O-glycans in pro-brain natriuretic peptide stability.

Clinical chemistry, 56(6), 959-66

Citation

Jiang, Jingjing; Pristera, Nicole; Wang, Wei; Zhang, Xiumei; Wu, Qingyu. (2010). Effect of sialylated O-glycans in pro-brain natriuretic peptide stability.. Clinical chemistry, 56(6), 959-66. https://doi.org/10.1373/clinchem.2009.140558