Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the ghrelin system mediates nicotine's rewarding/addictive properties.
Key findingGhrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the
What the researchers found
Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the ghrelin system mediates nicotine's rewarding/addictive properties.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice.
Drug and alcohol dependence, 117(2-3), 126-31
Citation
Jerlhag, Elisabet; Engel, Jörgen A. (2011). Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice.. Drug and alcohol dependence, 117(2-3), 126-31. https://doi.org/10.1016/j.drugalcdep.2011.01.010