Blocking Ghrelin Receptors Reduces Nicotine's Rewarding Effects: Ghrelin in Nicotine Addiction
Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the ghrelin system mediates nicotine's rewarding/addictive properties.
Quick Facts
What This Study Found
Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the ghrelin system mediates nicotine's rewarding/addictive properties.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2011.
- Original Title:
- Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice.
- Published In:
- Drug and alcohol dependence, 117(2-3), 126-31 (2011)
- Authors:
- Jerlhag, Elisabet(10), Engel, Jörgen A(3)
- Database ID:
- RPEP-01785
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Blocking Ghrelin Receptors Reduces Nicotine's Rewarding Effects: Ghrelin in Nicotine Addiction
What was found?
Ghrelin receptor antagonism attenuated nicotine-induced locomotor stimulation, dopamine release, and conditioned place preference — demonstrating the ghrelin system mediates nicotine's rewarding/addictive properties.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01785APA
Jerlhag, Elisabet; Engel, Jörgen A. (2011). Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice.. Drug and alcohol dependence, 117(2-3), 126-31. https://doi.org/10.1016/j.drugalcdep.2011.01.010
MLA
Jerlhag, Elisabet, et al. "Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice.." Drug and alcohol dependence, 2011. https://doi.org/10.1016/j.drugalcdep.2011.01.010
RethinkPeptides
RethinkPeptides Research Database. "Ghrelin receptor antagonism attenuates nicotine-induced loco..." RPEP-01785. Retrieved from https://rethinkpeptides.com/research/jerlhag-2011-ghrelin-receptor-antagonism-attenuates
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.