Liposomes encapsulating novel antimicrobial peptide Omiganan: Characterization and its pharmacodynamic evaluation in atopic dermatitis and psoriasis mice model.
Quick Facts
What This Study Found
Omiganan liposomal gel reduced pro-inflammatory cytokines and improved skin lesions significantly compared to conventional formulations.
Key Numbers
How They Did This
The study involved creating liposomes encapsulating Omiganan and evaluating their efficacy in mice models of atopic dermatitis and psoriasis.
Why This Research Matters
This research highlights a potential new treatment for chronic skin conditions, which can significantly impact patients' quality of life. The findings could lead to better therapeutic options in dermatology.
What This Study Doesn't Tell Us
The study was conducted in mice, and results may not directly translate to humans. Further clinical trials are needed.
Trust & Context
- Original Title:
- Liposomes encapsulating novel antimicrobial peptide Omiganan: Characterization and its pharmacodynamic evaluation in atopic dermatitis and psoriasis mice model.
- Published In:
- International journal of pharmaceutics, 624, 122045 (2022)
- Authors:
- Javia, Ankit, Misra, Ambikanandan, Thakkar, Hetal
- Database ID:
- RPEP-06225
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06225APA
Javia, Ankit; Misra, Ambikanandan; Thakkar, Hetal. (2022). Liposomes encapsulating novel antimicrobial peptide Omiganan: Characterization and its pharmacodynamic evaluation in atopic dermatitis and psoriasis mice model.. International journal of pharmaceutics, 624, 122045. https://doi.org/10.1016/j.ijpharm.2022.122045
MLA
Javia, Ankit, et al. "Liposomes encapsulating novel antimicrobial peptide Omiganan: Characterization and its pharmacodynamic evaluation in atopic dermatitis and psoriasis mice model.." International journal of pharmaceutics, 2022. https://doi.org/10.1016/j.ijpharm.2022.122045
RethinkPeptides
RethinkPeptides Research Database. "Liposomes encapsulating novel antimicrobial peptide Omiganan..." RPEP-06225. Retrieved from https://rethinkpeptides.com/research/javia-2022-liposomes-encapsulating-novel-antimicrobial
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.