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Study breakdown

BPC-157 Protects Against Diclofenac-Induced Multi-Organ Damage: Gut, Liver, and Brain

evidence
The takeaway

BPC-157 attenuated diclofenac-induced gastrointestinal, liver, and encephalopathy damage in rats — comprehensive multi-organ NSAID toxicity protection from a single peptide agent.

Key finding

BPC-157 attenuated diclofenac-induced gastrointestinal, liver, and encephalopathy damage in rats — comprehensive multi-organ NSAID toxicity protection

What the researchers found

BPC-157 attenuated diclofenac-induced gastrointestinal, liver, and encephalopathy damage in rats — comprehensive multi-organ NSAID toxicity protection from a single peptide agent.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
BPC-157 Protects Against Diclofenac-Induced Multi-Organ Damage: Gut, Liver, and Brain
What was found?
BPC-157 attenuated diclofenac-induced gastrointestinal, liver, and encephalopathy damage in rats — comprehensive multi-organ NSAID toxicity protection from a single peptide agent.

Read the original research

Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions.

Life sciences, 88(11-12), 535-42

Citation

Ilic, Spomenko; Drmic, Domagoj; Franjic, Sandra; Kolenc, Danijela; Coric, Marijana; Brcic, Luka; Klicek, Robert; Radic, Bozo; Sever, Marko; Djuzel, Viktor; Filipovic, Marinko; Djakovic, Zeljko; Stambolija, Vasilije; Blagaic, Alenka Boban; Zoricic, Ivan; Gjurasin, Miroslav; Stupnisek, Mirjana; Romic, Zeljko; Zarkovic, Kamelija; Dzidic, Senka; Seiwerth, Sven; Sikiric, Predrag. (2011). Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions.. Life sciences, 88(11-12), 535-42. https://doi.org/10.1016/j.lfs.2011.01.015