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Study breakdown

BPC-157 Protects Against Ibuprofen-Induced Liver Damage and Brain Swelling in Rats

evidence
The takeaway

BPC-157 counteracted ibuprofen-induced hepatic encephalopathy, hepatomegaly, and gastric lesions in rats — protecting liver, brain, AND stomach from NSAID toxicity simultaneously.

Key finding

BPC-157 counteracted ibuprofen-induced hepatic encephalopathy, hepatomegaly, and gastric lesions in rats — protecting liver, brain, AND stomach from N

What the researchers found

BPC-157 counteracted ibuprofen-induced hepatic encephalopathy, hepatomegaly, and gastric lesions in rats — protecting liver, brain, AND stomach from NSAID toxicity simultaneously.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
BPC-157 Protects Against Ibuprofen-Induced Liver Damage and Brain Swelling in Rats
What was found?
BPC-157 counteracted ibuprofen-induced hepatic encephalopathy, hepatomegaly, and gastric lesions in rats — protecting liver, brain, AND stomach from NSAID toxicity simultaneously.

Read the original research

Ibuprofen hepatic encephalopathy, hepatomegaly, gastric lesion and gastric pentadecapeptide BPC 157 in rats.

European journal of pharmacology, 667(1-3), 322-9

Citation

Ilic, Spomenko; Drmic, Domagoj; Zarkovic, Kamelija; Kolenc, Danijela; Brcic, Luka; Radic, Bozo; Djuzel, Viktor; Blagaic, Alenka Boban; Romic, Zeljko; Dzidic, Senka; Kalogjera, Livije; Seiwerth, Sven; Sikiric, Predrag. (2011). Ibuprofen hepatic encephalopathy, hepatomegaly, gastric lesion and gastric pentadecapeptide BPC 157 in rats.. European journal of pharmacology, 667(1-3), 322-9. https://doi.org/10.1016/j.ejphar.2011.05.038