BPC-157 Protects Against Paracetamol Overdose Brain Damage and Seizures in Rats

BPC-157 counteracted high-dose paracetamol-induced brain damage, seizures, and hepatotoxicity in rats — adding acetaminophen overdose protection to its expanding organ protection profile.

RPEP-016302010RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

BPC-157 counteracted high-dose paracetamol-induced brain damage, seizures, and hepatotoxicity in rats — adding acetaminophen overdose protection to its expanding organ protection profile.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding BPC-157 counteracted high-dose paracetamol-induced brain damage, seizures, and hepatotoxicity in rats — adding acetaminophen overdose protection to it
Evidence Grade:
emerging evidence.
Study Age:
Published in 2010.
Original Title:
High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736).
Published In:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 61(2), 241-50 (2010)
Database ID:
RPEP-01630

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

BPC-157 Protects Against Paracetamol Overdose Brain Damage and Seizures in Rats

What was found?

BPC-157 counteracted high-dose paracetamol-induced brain damage, seizures, and hepatotoxicity in rats — adding acetaminophen overdose protection to its expanding organ protection profile.

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Cite This Study

RPEP-01630·https://rethinkpeptides.com/research/RPEP-01630

APA

Ilic, S; Drmic, D; Zarkovic, K; Kolenc, D; Coric, M; Brcic, L; Klicek, R; Radic, B; Sever, M; Djuzel, V; Ivica, M; Boban Blagaic, A; Zoricic, Z; Anic, T; Zoricic, I; Djidic, S; Romic, Z; Seiwerth, S; Sikiric, P. (2010). High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736).. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 61(2), 241-50.

MLA

Ilic, S, et al. "High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736).." Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010.

RethinkPeptides

RethinkPeptides Research Database. "High hepatotoxic dose of paracetamol produces generalized co..." RPEP-01630. Retrieved from https://rethinkpeptides.com/research/ilic-2010-high-hepatotoxic-dose-of

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.