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Study breakdown

Menopause, Estradiol, and Peptide Type All Independently Determine GH Pulse Response in Women

evidence
The takeaway

Pre- versus postmenopausal status, estradiol levels, and GH secretagogue type each independently determined pulsatile GH secretion patterns in women — all three factors must be considered for optimal GH therapy.

Key finding

Pre- versus postmenopausal status, estradiol levels, and GH secretagogue type each independently determined pulsatile GH secretion patterns in women —

What the researchers found

Pre- versus postmenopausal status, estradiol levels, and GH secretagogue type each independently determined pulsatile GH secretion patterns in women — all three factors must be considered for optimal GH therapy.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Menopause, Estradiol, and Peptide Type All Independently Determine GH Pulse Response in Women
What was found?
Pre- versus postmenopausal status, estradiol levels, and GH secretagogue type each independently determined pulsatile GH secretion patterns in women — all three factors must be considered for optimal GH therapy.

Read the original research

Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp.

The Journal of clinical endocrinology and metabolism, 95(1), 353-60

Citation

Hudson, Susan B; Schroeder, Darrell R; Bailey, Joy N; Mielke, Kristi L; Erickson, Dana; Miles, John M; Bowers, Cyril Y; Veldhuis, Johannes D. (2010). Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp.. The Journal of clinical endocrinology and metabolism, 95(1), 353-60. https://doi.org/10.1210/jc.2009-1769