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Study breakdown

Opioid Receptors in the GI Tract: The Complete Guide to Gut Opioid Pharmacology

evidence
The takeaway

Comprehensive review of mu, delta, and kappa opioid receptor distribution and function throughout the GI tract, explaining how opioid drugs cause constipation and how peripheral opioid antagonists can treat it.

Key finding

Comprehensive review of mu, delta, and kappa opioid receptor distribution and function throughout the GI tract, explaining how opioid drugs cause cons

What the researchers found

Comprehensive review of mu, delta, and kappa opioid receptor distribution and function throughout the GI tract, explaining how opioid drugs cause constipation and how peripheral opioid antagonists can treat it.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Opioid Receptors in the GI Tract: The Complete Guide to Gut Opioid Pharmacology
What was found?
Comprehensive review of mu, delta, and kappa opioid receptor distribution and function throughout the GI tract, explaining how opioid drugs cause constipation and how peripheral opioid antagonists can treat it.

Read the original research

Opioid receptors in the gastrointestinal tract.

Regulatory peptides, 155(1-3), 11-7

Citation

Holzer, Peter. (2009). Opioid receptors in the gastrointestinal tract.. Regulatory peptides, 155(1-3), 11-7. https://doi.org/10.1016/j.regpep.2009.03.012