CCK stimulated hypothalamic GLP-1 neurons through alpha-1 adrenoceptor-mediated glutamatergic synaptic input, revealing how two gut satiety signals converge in the brain for integrated appetite control.
Key findingCCK stimulated hypothalamic GLP-1 neurons through alpha-1 adrenoceptor-mediated glutamatergic synaptic input, revealing how two gut satiety signals co
What the researchers found
CCK stimulated hypothalamic GLP-1 neurons through alpha-1 adrenoceptor-mediated glutamatergic synaptic input, revealing how two gut satiety signals converge in the brain for integrated appetite control.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.
Diabetes, 60(11), 2701-9
Citation
Hisadome, Kazunari; Reimann, Frank; Gribble, Fiona M; Trapp, Stefan. (2011). CCK stimulation of GLP-1 neurons involves α1-adrenoceptor-mediated increase in glutamatergic synaptic inputs.. Diabetes, 60(11), 2701-9. https://doi.org/10.2337/db11-0489