Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular mechanism by which dairy peptides lower blood pressure.
Key findingCasein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular
What the researchers found
Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular mechanism by which dairy peptides lower blood pressure.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings.
Heart and vessels, 26(5), 549-56
Citation
Hirota, Tatsuhiko; Nonaka, Atsuko; Matsushita, Akiko; Uchida, Naoto; Ohki, Kohji; Asakura, Masanori; Kitakaze, Masafumi. (2011). Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings.. Heart and vessels, 26(5), 549-56. https://doi.org/10.1007/s00380-010-0096-y