Milk Blood Pressure Peptides VPP and IPP Relax Blood Vessels Through Nitric Oxide Production

Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular mechanism by which dairy peptides lower blood pressure.

Hirota, Tatsuhiko et al.·Heart and vessels·2011·
RPEP-017782011RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular mechanism by which dairy peptides lower blood pressure.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular
Evidence Grade:
emerging evidence.
Study Age:
Published in 2011.
Original Title:
Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings.
Published In:
Heart and vessels, 26(5), 549-56 (2011)
Database ID:
RPEP-01778

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Milk Blood Pressure Peptides VPP and IPP Relax Blood Vessels Through Nitric Oxide Production

What was found?

Casein-derived tripeptides VPP and IPP stimulated endothelial nitric oxide production and produced endothelium-dependent vasodilation — the molecular mechanism by which dairy peptides lower blood pressure.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01778·https://rethinkpeptides.com/research/RPEP-01778

APA

Hirota, Tatsuhiko; Nonaka, Atsuko; Matsushita, Akiko; Uchida, Naoto; Ohki, Kohji; Asakura, Masanori; Kitakaze, Masafumi. (2011). Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings.. Heart and vessels, 26(5), 549-56. https://doi.org/10.1007/s00380-010-0096-y

MLA

Hirota, Tatsuhiko, et al. "Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings.." Heart and vessels, 2011. https://doi.org/10.1007/s00380-010-0096-y

RethinkPeptides

RethinkPeptides Research Database. "Milk casein-derived tripeptides, VPP and IPP induced NO prod..." RPEP-01778. Retrieved from https://rethinkpeptides.com/research/hirota-2011-milk-caseinderived-tripeptides-vpp

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.