Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-cGAMP Complex.
Quick Facts
What This Study Found
The new delivery system improved T cell priming and antitumoral response in a mouse model.
Key Numbers
How They Did This
The study involved creating a peptide-STINGΔTM-cGAMP complex and testing its effectiveness in vitro and in vivo using a mouse model.
Why This Research Matters
Improving peptide vaccine delivery could significantly enhance cancer immunotherapy outcomes. This method addresses challenges in vaccine transport and immune activation.
What This Study Doesn't Tell Us
The study was conducted in mice, and results may not directly translate to humans.
Trust & Context
- Original Title:
- Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-cGAMP Complex.
- Published In:
- Advanced healthcare materials, 11(15), e2200905 (2022)
- Authors:
- He, Yanpu, Hong, Celestine, Fletcher, Samantha J, Berger, Adam G, Sun, Xin, Yang, Mengdi, Huang, Shengnan, Belcher, Angela M, Irvine, Darrell J, Li, Jiahe, Hammond, Paula T
- Database ID:
- RPEP-06179
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06179APA
He, Yanpu; Hong, Celestine; Fletcher, Samantha J; Berger, Adam G; Sun, Xin; Yang, Mengdi; Huang, Shengnan; Belcher, Angela M; Irvine, Darrell J; Li, Jiahe; Hammond, Paula T. (2022). Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-cGAMP Complex.. Advanced healthcare materials, 11(15), e2200905. https://doi.org/10.1002/adhm.202200905
MLA
He, Yanpu, et al. "Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-cGAMP Complex.." Advanced healthcare materials, 2022. https://doi.org/10.1002/adhm.202200905
RethinkPeptides
RethinkPeptides Research Database. "Peptide-Based Cancer Vaccine Delivery via the STINGΔTM-cGAMP..." RPEP-06179. Retrieved from https://rethinkpeptides.com/research/he-2022-peptidebased-cancer-vaccine-delivery
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.