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Study breakdown

Pharmacology of Appetite Management for Obesity in 2010: GLP-1, CB1, and Combination Approaches

evidence
The takeaway

Updated review of appetite pharmacology for obesity: GLP-1 agonists (most promising), cannabinoid CB1 antagonists (withdrawn for psychiatric side effects), and combination peptide approaches — the 2010 drug development landscape.

Key finding

Updated review of appetite pharmacology for obesity: GLP-1 agonists (most promising), cannabinoid CB1 antagonists (withdrawn for psychiatric side effe

What the researchers found

Updated review of appetite pharmacology for obesity: GLP-1 agonists (most promising), cannabinoid CB1 antagonists (withdrawn for psychiatric side effects), and combination peptide approaches — the 2010 drug development landscape.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Pharmacology of Appetite Management for Obesity in 2010: GLP-1, CB1, and Combination Approaches
What was found?
Updated review of appetite pharmacology for obesity: GLP-1 agonists (most promising), cannabinoid CB1 antagonists (withdrawn for psychiatric side effects), and combination peptide approaches — the 2010 drug development landscape.

Read the original research

Pharmacological management of appetite expression in obesity.

Nature reviews. Endocrinology, 6(5), 255-69

Citation

Halford, Jason C G; Boyland, Emma J; Blundell, John E; Kirkham, Tim C; Harrold, Joanne A. (2010). Pharmacological management of appetite expression in obesity.. Nature reviews. Endocrinology, 6(5), 255-69. https://doi.org/10.1038/nrendo.2010.19