GLP-2 reduced intestinal permeability in NOD mice but did not prevent type 1 diabetes onset, separating gut barrier repair from autoimmune diabetes prevention — gut healing alone doesn't prevent autoimmunity.
Key findingGLP-2 reduced intestinal permeability in NOD mice but did not prevent type 1 diabetes onset, separating gut barrier repair from autoimmune diabetes pr
What the researchers found
GLP-2 reduced intestinal permeability in NOD mice but did not prevent type 1 diabetes onset, separating gut barrier repair from autoimmune diabetes prevention — gut healing alone doesn't prevent autoimmunity.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Glucagon-like peptide-2 reduces intestinal permeability but does not modify the onset of type 1 diabetes in the nonobese diabetic mouse.
Endocrinology, 150(2), 592-9
Citation
Hadjiyanni, Irene; Li, Kunmin Karen; Drucker, Daniel J. (2009). Glucagon-like peptide-2 reduces intestinal permeability but does not modify the onset of type 1 diabetes in the nonobese diabetic mouse.. Endocrinology, 150(2), 592-9. https://doi.org/10.1210/en.2008-1228