Comprehensive review of nicotine-opioid interactions: nicotine releases endogenous opioids, modulates opioid receptor function, and shares reward pathways — explaining co-addiction and nicotine's pain-modifying effects.
Key findingComprehensive review of nicotine-opioid interactions: nicotine releases endogenous opioids, modulates opioid receptor function, and shares reward path
What the researchers found
Comprehensive review of nicotine-opioid interactions: nicotine releases endogenous opioids, modulates opioid receptor function, and shares reward pathways — explaining co-addiction and nicotine's pain-modifying effects.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2011.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Nicotine and endogenous opioids: neurochemical and pharmacological evidence.
Neuropharmacology, 60(7-8), 1209-20
Citation
Hadjiconstantinou, Maria; Neff, Norton H. (2011). Nicotine and endogenous opioids: neurochemical and pharmacological evidence.. Neuropharmacology, 60(7-8), 1209-20. https://doi.org/10.1016/j.neuropharm.2010.11.010