Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.

RPEP-069252023Guerlavais, Vincent; Sawyer, Tomi K; Carvajal, Luis; Chang, Yong S; Graves, Bradford; Ren, Jian-Guo; Sutton, David; Olson, Karen A; Packman, Kathryn; Darlak, Krzysztof; Elkin, Carl; Feyfant, Eric; Kesavan, Kamala; Gangurde, Pranoti; Vassilev, Lyubomir T; Nash, Huw M; Vukovic, Vojislav; Aivado, Manuel; Annis, D Allen

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Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.

Journal of medicinal chemistry, 66(14), 9401-9417

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Guerlavais, Vincent; Sawyer, Tomi K; Carvajal, Luis; Chang, Yong S; Graves, Bradford; Ren, Jian-Guo; Sutton, David; Olson, Karen A; Packman, Kathryn; Darlak, Krzysztof; Elkin, Carl; Feyfant, Eric; Kesavan, Kamala; Gangurde, Pranoti; Vassilev, Lyubomir T; Nash, Huw M; Vukovic, Vojislav; Aivado, Manuel; Annis, D Allen. (2023). Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.. Journal of medicinal chemistry, 66(14), 9401-9417. https://doi.org/10.1021/acs.jmedchem.3c00623