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Different Proteins Trigger Different Satiety Hormones — And It Differs Between Humans and Mice

evidence
The takeaway

Specific dietary proteins released different patterns of satiety hormones (GLP-1, CCK, PYY) from human versus mouse intestinal cells, highlighting species differences that affect translating appetite research from animals to humans.

Key finding

Specific dietary proteins released different patterns of satiety hormones (GLP-1, CCK, PYY) from human versus mouse intestinal cells, highlighting spe

What the researchers found

Specific dietary proteins released different patterns of satiety hormones (GLP-1, CCK, PYY) from human versus mouse intestinal cells, highlighting species differences that affect translating appetite research from animals to humans.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Different Proteins Trigger Different Satiety Hormones — And It Differs Between Humans and Mice
What was found?
Specific dietary proteins released different patterns of satiety hormones (GLP-1, CCK, PYY) from human versus mouse intestinal cells, highlighting species differences that affect translating appetite research from animals to humans.

Read the original research

Release of satiety hormones in response to specific dietary proteins is different between human and murine small intestinal mucosa.

Annals of nutrition & metabolism, 56(4), 308-13

Citation

Geraedts, Maartje C P; Troost, Freddy J; Tinnemans, Rik; Söderholm, Johan D; Brummer, Robert-Jan; Saris, Wim H M. (2010). Release of satiety hormones in response to specific dietary proteins is different between human and murine small intestinal mucosa.. Annals of nutrition & metabolism, 56(4), 308-13. https://doi.org/10.1159/000312664