Neuronal M3 muscarinic acetylcholine receptors were shown to be essential for somatotroph (GH cell) proliferation and normal body growth, revealing a cholinergic requirement for the GH axis.
Key findingNeuronal M3 muscarinic acetylcholine receptors were shown to be essential for somatotroph (GH cell) proliferation and normal body growth, revealing a
What the researchers found
Neuronal M3 muscarinic acetylcholine receptors were shown to be essential for somatotroph (GH cell) proliferation and normal body growth, revealing a cholinergic requirement for the GH axis.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth.
Proceedings of the National Academy of Sciences of the United States of America, 106(15), 6398-403
Citation
Gautam, Dinesh; Jeon, Jongrye; Starost, Matthew F; Han, Sung-Jun; Hamdan, Fadi F; Cui, Yinghong; Parlow, Albert F; Gavrilova, Oksana; Szalayova, Ildiko; Mezey, Eva; Wess, Jürgen. (2009). Neuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth.. Proceedings of the National Academy of Sciences of the United States of America, 106(15), 6398-403. https://doi.org/10.1073/pnas.0900977106