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Study breakdown

Making Cell-Penetrating Apoptotic Peptides From Natural Proteins for Cancer Therapy

evidence
The takeaway

Cell-permeable apoptotic peptides were chemically synthesized from in-vivo-produced protein sequences and shown to induce cancer cell death — converting natural death signals into synthetic cancer drugs.

Key finding

Cell-permeable apoptotic peptides were chemically synthesized from in-vivo-produced protein sequences and shown to induce cancer cell death — converti

What the researchers found

Cell-permeable apoptotic peptides were chemically synthesized from in-vivo-produced protein sequences and shown to induce cancer cell death — converting natural death signals into synthetic cancer drugs.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2011.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Making Cell-Penetrating Apoptotic Peptides From Natural Proteins for Cancer Therapy
What was found?
Cell-permeable apoptotic peptides were chemically synthesized from in-vivo-produced protein sequences and shown to induce cancer cell death — converting natural death signals into synthetic cancer drugs.

Read the original research

Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins.

Bioconjugate chemistry, 22(9), 1763-7

Citation

Fricke, Thomas; Mart, Robert J; Watkins, Catherine L; Wiltshire, Marie; Errington, Rachel J; Smith, Paul J; Jones, Arwyn T; Allemann, Rudolf K. (2011). Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins.. Bioconjugate chemistry, 22(9), 1763-7. https://doi.org/10.1021/bc200338u