Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.
Quick Facts
What This Study Found
153 conotoxin precursors from 23 superfamilies identified in C. taeniatus venom, with T, O1, M, and O2 superfamilies comprising 63.4% of total conotoxin diversity.
Key Numbers
234 peptide fragments; 153 conotoxin precursors; 23 superfamilies; 84% proteins 500-4,000 Da; T 22.87%, O1 17.65%, M 13.1%, O2 9.8%; 48 non-conotoxin proteins
How They Did This
Proteomic analysis using bioanalytical techniques including mass spectrometry. Classification of conotoxin precursors and non-conotoxin proteins.
Why This Research Matters
Each cone snail species has a unique venom profile. Cataloging understudied species expands the library of potential drug molecules, especially for pain and neurological conditions.
What This Study Doesn't Tell Us
Proteomic characterization only. No functional testing of individual peptides. Activities assigned by sequence similarity, not experimental verification.
Trust & Context
- Original Title:
- Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.
- Published In:
- The journal of venomous animals and toxins including tropical diseases, 27, e20210023 (2021)
- Authors:
- Fouda, Maged M A, Abdel-Wahab, Mohammed, Mohammadien, Amal, Germoush, Mousa O, Sarhan, Moustafa
- Database ID:
- RPEP-05388
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-05388APA
Fouda, Maged M A; Abdel-Wahab, Mohammed; Mohammadien, Amal; Germoush, Mousa O; Sarhan, Moustafa. (2021). Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.. The journal of venomous animals and toxins including tropical diseases, 27, e20210023. https://doi.org/10.1590/1678-9199-JVATITD-2021-0023
MLA
Fouda, Maged M A, et al. "Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.." The journal of venomous animals and toxins including tropical diseases, 2021. https://doi.org/10.1590/1678-9199-JVATITD-2021-0023
RethinkPeptides
RethinkPeptides Research Database. "Proteomic analysis of Red Sea Conus taeniatus venom reveals ..." RPEP-05388. Retrieved from https://rethinkpeptides.com/research/fouda-2021-proteomic-analysis-of-red
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.