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Research citation

Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.

In Vitro (Proteomics)Low evidence

This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.

What the researchers found

153 conotoxin precursors from 23 superfamilies identified in C. taeniatus venom, with T, O1, M, and O2 superfamilies comprising 63.4% of total conotoxin diversity.

Why it matters

Each cone snail species has a unique venom profile. Cataloging understudied species expands the library of potential drug molecules, especially for pain and neurological conditions.

The numbers in context

234 peptide fragments; 153 conotoxin precursors; 23 superfamilies; 84% proteins 500-4,000 Da; T 22.87%, O1 17.65%, M 13.1%, O2 9.8%; 48 non-conotoxin proteins

How the study worked

Proteomic analysis using bioanalytical techniques including mass spectrometry. Classification of conotoxin precursors and non-conotoxin proteins.

Who was studied

Conus taeniatus (Red Sea worm-hunting cone snail) venom analysis

What this study cannot tell us

Proteomic characterization only. No functional testing of individual peptides. Activities assigned by sequence similarity, not experimental verification.

Read the original research

Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.

The journal of venomous animals and toxins including tropical diseases, 27, e20210023

Citation

Fouda, Maged M A; Abdel-Wahab, Mohammed; Mohammadien, Amal; Germoush, Mousa O; Sarhan, Moustafa. (2021). Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications.. The journal of venomous animals and toxins including tropical diseases, 27, e20210023. https://doi.org/10.1590/1678-9199-JVATITD-2021-0023