rethinkPeptides Search
Menu
Study breakdown

Antimicrobial Peptides Kill the Chagas Disease Parasite: Synergistic Combination Approaches

evidence
The takeaway

Multiple antimicrobial peptides showed synergistic cytotoxicity against Trypanosoma cruzi (Chagas disease parasite) and host bacteria, identifying peptide combination therapy for this neglected tropical disease.

Key finding

Multiple antimicrobial peptides showed synergistic cytotoxicity against Trypanosoma cruzi (Chagas disease parasite) and host bacteria, identifying pep

What the researchers found

Multiple antimicrobial peptides showed synergistic cytotoxicity against Trypanosoma cruzi (Chagas disease parasite) and host bacteria, identifying peptide combination therapy for this neglected tropical disease.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Antimicrobial Peptides Kill the Chagas Disease Parasite: Synergistic Combination Approaches
What was found?
Multiple antimicrobial peptides showed synergistic cytotoxicity against Trypanosoma cruzi (Chagas disease parasite) and host bacteria, identifying peptide combination therapy for this neglected tropical disease.

Read the original research

Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts.

Experimental parasitology, 125(4), 342-7

Citation

Fieck, Annabeth; Hurwitz, Ivy; Kang, Angray S; Durvasula, Ravi. (2010). Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts.. Experimental parasitology, 125(4), 342-7. https://doi.org/10.1016/j.exppara.2010.02.016