Unexpected role for IGF-1 in starvation: Maintenance of blood glucose.
Quick Facts
What This Study Found
Starved ghrelin-deficient mice had a 90% reduction in plasma IGF-1 compared to wild-type mice.
Key Numbers
How They Did This
The study involved comparing wild-type mice and ghrelin-deficient mice under starvation conditions, measuring plasma IGF-1 levels and glucose production.
Why This Research Matters
Understanding how IGF-1 functions during starvation could inform treatments for metabolic disorders and improve our knowledge of energy regulation.
What This Study Doesn't Tell Us
The study was conducted in mice, and results may not directly translate to humans.
Trust & Context
- Original Title:
- Unexpected role for IGF-1 in starvation: Maintenance of blood glucose.
- Published In:
- Proceedings of the National Academy of Sciences of the United States of America, 119(32), e2208855119 (2022)
- Database ID:
- RPEP-06116
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06116APA
Fang, Fei; Goldstein, Joseph L; Shi, Xuanming; Liang, Guosheng; Brown, Michael S. (2022). Unexpected role for IGF-1 in starvation: Maintenance of blood glucose.. Proceedings of the National Academy of Sciences of the United States of America, 119(32), e2208855119. https://doi.org/10.1073/pnas.2208855119
MLA
Fang, Fei, et al. "Unexpected role for IGF-1 in starvation: Maintenance of blood glucose.." Proceedings of the National Academy of Sciences of the United States of America, 2022. https://doi.org/10.1073/pnas.2208855119
RethinkPeptides
RethinkPeptides Research Database. "Unexpected role for IGF-1 in starvation: Maintenance of bloo..." RPEP-06116. Retrieved from https://rethinkpeptides.com/research/fang-2022-unexpected-role-for-igf1
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.