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Study breakdown

Apelin Peptide Protects the Heart in Pulmonary Hypertension

evidence
The takeaway

Apelin decreased right ventricular injury and improved cardiac function in monocrotaline-induced pulmonary hypertension rats, establishing apelin as a cardioprotective peptide for pulmonary hypertension.

Key finding

Apelin decreased right ventricular injury and improved cardiac function in monocrotaline-induced pulmonary hypertension rats, establishing apelin as a

What the researchers found

Apelin decreased right ventricular injury and improved cardiac function in monocrotaline-induced pulmonary hypertension rats, establishing apelin as a cardioprotective peptide for pulmonary hypertension.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2009.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Apelin Peptide Protects the Heart in Pulmonary Hypertension
What was found?
Apelin decreased right ventricular injury and improved cardiac function in monocrotaline-induced pulmonary hypertension rats, establishing apelin as a cardioprotective peptide for pulmonary hypertension.

Read the original research

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

American journal of physiology. Heart and circulatory physiology, 296(6), H2007-14

Citation

Falcão-Pires, Inês; Gonçalves, Nádia; Henriques-Coelho, Tiago; Moreira-Gonçalves, Daniel; Roncon-Albuquerque, Roberto; Leite-Moreira, Adelino F. (2009). Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.. American journal of physiology. Heart and circulatory physiology, 296(6), H2007-14. https://doi.org/10.1152/ajpheart.00089.2009