Short Anticancer Peptides Escape Cancer's Heparan Sulfate Shield
Smaller lytic anticancer peptides evaded the heparan sulfate barrier on cancer cell surfaces that inhibited larger peptides — size optimization enables effective cancer cell membrane disruption despite surface shielding.
Quick Facts
What This Study Found
Smaller lytic anticancer peptides evaded the heparan sulfate barrier on cancer cell surfaces that inhibited larger peptides — size optimization enables effective cancer cell membrane disruption despite surface shielding.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding Smaller lytic anticancer peptides evaded the heparan sulfate barrier on cancer cell surfaces that inhibited larger peptides — size optimization enable
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2011.
- Original Title:
- Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells.
- Published In:
- BMC cancer, 11, 116 (2011)
- Authors:
- Fadnes, Bodil(2), Uhlin-Hansen, Lars(2), Lindin, Inger(2), Rekdal, Øystein
- Database ID:
- RPEP-01756
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Short Anticancer Peptides Escape Cancer's Heparan Sulfate Shield
What was found?
Smaller lytic anticancer peptides evaded the heparan sulfate barrier on cancer cell surfaces that inhibited larger peptides — size optimization enables effective cancer cell membrane disruption despite surface shielding.
Read More on RethinkPeptides
Related articles coming soon.
Cite This Study
https://rethinkpeptides.com/research/RPEP-01756APA
Fadnes, Bodil; Uhlin-Hansen, Lars; Lindin, Inger; Rekdal, Øystein. (2011). Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells.. BMC cancer, 11, 116. https://doi.org/10.1186/1471-2407-11-116
MLA
Fadnes, Bodil, et al. "Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells.." BMC cancer, 2011. https://doi.org/10.1186/1471-2407-11-116
RethinkPeptides
RethinkPeptides Research Database. "Small lytic peptides escape the inhibitory effect of heparan..." RPEP-01756. Retrieved from https://rethinkpeptides.com/research/fadnes-2011-small-lytic-peptides-escape
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.